pH Dependence of Choline Esterase Activity at Various Substrate and Inhibitor Concentrations.
نویسندگان
چکیده
منابع مشابه
The Choline-esterase Activity of the Blood Serum in Disease.
The investigations of Dale and his coworkers (1, 2) on the chemical transmission of parasympathetic nerve stimulation and of Walker (3, 4) on the use of physostigmine and prostigmin in myasthenia gravis have stimulated interest in the choline-esterase activity of serum. Lucas, Hall, and Ettinger (5) studied the serum esterase activity of 200 subjects and obtained results that were in essential ...
متن کاملA comparison of the choline-esterase activities of the blood-sera from various species.
IT was recently shown by Stedman, Stedman and Easson [1932] that, whereas liver esterase and pancreatic lipase are without appreciable action on esters of choline, there is present in the blood-serum of the horse an enzyme which readily hydrolyses such esters, but which exerts little, if any, action on simple esters such as methyl butyrate. In order to emphasise the specific nature of its activ...
متن کاملStudies on the Specificity of Choline Esterase
The present investigation was undertaken to determine the relation between the structure of various substrates and the action of serum choline esterase upon them. The comparison of activities with different esters should take into account two factors : the hydrolytic velocities compared should be linear functions of time, and these velocities should be independent of substrate concentration. Th...
متن کاملOn The Physiological Significance of Choline Esterase *
During the last 20 years evidence has accumulated, mainly from the work of 0. Loewi, Dale, Cannon and their co-workers, supporting the view that the action of sympathetic and parasympathetic nerves on the effector organ occurs by virtue of chemical mediation. It is generally believed that adrenaline, or a related substance, sympathin, is the transmitter substance at sympathetic nerve endings, w...
متن کاملCccv. the Purification of Choline-esterase
ALTHOUGH it was previously known from pharmacological experiments, quoted in our earlier papers, that certain body fluids brought about the enzymic decomposition of small amounts of acetylcholine, the first demonstration of the existence of a specific enzyme which catalyses the hydrolysis of this ester, as well as of other esters of choline, was that of Stedman et al. [1932] who termed the enzy...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1954
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.08-1368